Gene List

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Gene List
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Symbol Type Of Gene Taxonomy ID Gene ID Description View
CST2 - The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while … View
WFDC6 - This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, … View
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WNK2 - The protein encoded by this gene is a cytoplasmic serine-threonine kinase that contains cysteine in place of the lysine found … View
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ERVWE1 - Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are … View
AOC3 - Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The … View
- - This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal … View
PTGER3 - The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of … View
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PDE10A - Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This enzyme can hydrolyze both cAMP … View
ZNF7 - May function as a transcription factor. View
TOMM22 - The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts … View
GNRH2 - The protein encoded by this gene is a preproprotein that is cleaved to form a secreted 10 aa peptide hormone. … View
LHFPL2 - - View
ITGAE - ITGAE encodes integrin alpha chain E. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta … View
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PEX26 - Probably required for protein import into peroxisomes. Anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase … View
RNF168 - - View
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ALMS1 - This gene encodes a protein containing a large tandem-repeat domain that contains no cysteine residues. Mutations in this gene have … View
FAM60A - - View
C9orf53 - - View
LIM2 - The mammalian lens fiber cell membrane contains 5 major proteins ranging from 70 kD to 19 kD in size. The … View
EXOSC6 - This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition … View
GCNT2 - The enzyme encoded by this gene is responsible for the formation of the blood group I antigen. The i and … View
CITED4 - CITED4 belongs to a family of transcriptional coactivators that bind several proteins, including CREB-binding protein (MIM 600140) and p300 (MIM … View
SLC9A6 - Electroneutral exchange of protons for Na(+) and K(+) across the mitochondrial inner membrane. Contributes to organellar volume and calcium homeostasis. View
RLN3 - Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic … View
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IPO7 - The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein … View
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COX10 - Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c … View
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DBH - The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is … View
SLCO1C1 - Mediates the Na(+)-independent high affinity transport of organic anions such as the thyroid hormones thyroxine (T4) and rT3. Other potential … View
ARHGAP18 - - View
XRCC2 - This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and … View
ADCY3 - This gene encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic … View
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PGK2 - - View
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FAIM3 - - View
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NEFL - Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. View
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RPL34P2 - - View
EPPK1 - - View
MCF2L2 - - View
- - Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the … View
IL6R - Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in … View
KIAA1596 - - View
BPY2 - This gene is located in the nonrecombining portion of the Y chromosome, and expressed specifically in testis. The encoded protein … View
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SLC26A3 - The protein encoded by this gene is a transmembrane glycoprotein that functions as a sulfate transporter. It is localized to … View
GPR101 - G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM] View
GPR39 - - View
GNG8 - Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and … View
RTN4R - This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition … View
SPARCL1 - - View
PSME3 - The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core … View
FAF1 - Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number … View
ZNF663 - - View
- - This intronless gene is located upstream of the WT1 gene; these two genes are bi-directionally transcribed from the same promoter … View
CAPN2 - The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The … View
CCL24 - This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in … View
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SUV39H2 - Histone methyltransferase. Methylates Lys-9 of histone H3 and weakly histone H1 (in vitro). H3 Lys-9 methylation represents a specific tag … View
C14orf130 - - View
FANCG - FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region … View
LRIG3 - - View
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FOXB1 - - View
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NID2 - Basement membranes, which are composed of type IV collagens (see MIM 120130), laminins (see LAMC1; MIM 150290), perlecan (HSPG2; MIM … View
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PLXNB3 - Receptor for SEMA5A. Plays a role in axon guidance, invasive growth and cell migration. View
TRIM36 - The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three … View
ANXA6 - Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly … View
ADRA2C - Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. … View
AFG3L2 - This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an … View
CTBP2 - This gene produces two transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is … View
STAMBP - Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an … View
MTA3 - Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent … View
CRYGB - Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate … View
APOC1 - The protein encoded by this gene is a member of the apolipoprotein C1 family. This gene is expressed primarily in … View
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CRI2 - - View
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IL10 - The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. … View
RPL10L - This gene encodes a protein sharing sequence similarity with ribosomal protein L10. It is not currently known whether the encoded … View
RFPL1 - - View
ENPP4 - - View
HD - Huntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is … View
PTAR1 - - View
FCRL4 - - View
CNOT6 - The protein encoded by this gene is a subunit of the CCR4-NOT core transcriptional regulation complex. The encoded protein has … View
MAL2 - - View
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ACRC - - View
IL11 - The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly … View
- - May have nucleic acid binding capability that may participate in important transcriptional or translational control of cell growth, metabolism and … View
C10orf40 - - View
EFTUD1 - - View
TCF19 - Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of … View
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CDS1 - Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating … View
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TAS2R8 - This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These … View
NT5C - Pyrimidine 5-prime nucleotidase (P5N; EC 3.1.3.5), also called uridine 5-prime monophosphate hydrolase (UMPH), catalyzes the dephosphorylation of the pyrimidine 5-prime … View
ACSL4 - The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate … View
BAT2 - A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. … View
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SFRS5 - Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. View
HABP2 - The protein encoded by this gene is an extracellular serine protease which binds hyaluronic acid. It is involved in cell … View
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ZNF655 - This gene encodes a zinc finger protein. The zinc finger proteins are involved in DNA binding and protein-protein interactions. Multiple … View
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NCF1 - NCF1 encodes neutrophil cytosolic facter 1, the 47-kilodalton cytosolic subunit of the multi-protein complex known as NADPH oxidase found in … View
ST8SIA1 - Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of … View
COQ3 - - View
DNM1 - Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of … View
DMAP1 - Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following … View
RPA4 - - View
ILVBL - The protein encoded by this gene shares similarity with several thiamine pyrophosphate-binding proteins identified in bacteria, yeast, and plants. The … View
MYH6 - Muscle contraction. View
TMEM16C - - View
LPP - - View
MUC17 - Membrane mucins, such as MUC17, function in epithelial cells to provide cytoprotection, maintain luminal structure, provide signal transduction, and confer … View
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TRIP6 - - View
LRRC19 - - View
CAV3 - This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most … View
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CASZ1 - Probable transcription factor (By similarity). View
SCARF1 - The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells and mediates the binding … View
MIP - Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family … View
ZCCHC5 - - View
ECHDC3 - - View
BACE2 - Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of … View
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- - This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought … View
HTLF - Human T-cell leukemia virus enhancer factor (HTLF) may be a forkhead domain binding protein. It may function in the transcriptional … View
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AANAT - Arylalkylamine N-acetyltransferase belongs to the superfamily of acetyltransferases. It is the penultimate enzyme in melatonin synthesis and controls the night/day … View
HSD17B1 - Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH. View
UBA52 - Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation … View
ZNF439 - May be involved in transcriptional regulation. View
AATF - The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known … View
COL8A2 - Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. View
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SGCG - Gamma-sarcoglycan is one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin, probably to provide a link between the membrane … View
C16orf30 - - View
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THSD2 - This gene encodes a protein similar to thrombospondin type 1 domain-containing proteins. In addition, the protein contains a furin-like cysteine-rich … View
TMSB4X - This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also … View
COL12A1 - This gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril-associated collagens with interrupted triple … View
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PLA2G5 - - View
RBP4 - This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. … View
PWWP2 - - View
SPAG10 - - View
PGBD4 - The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon … View
PHF1 - This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD … View
TOM1L1 - Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it … View
SPAG11 - This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they … View
SREBF2 - This gene encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded … View
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AIM1 - May function as suppressor of malignant melanoma. It may exert its effects through interactions with the cytoskeleton. View
SMARCD2 - The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and … View
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C17orf35 - The function of putative receptor protein is unknown. View
TERF1 - This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present … View
NPHP1 - This gene encodes a protein with src homology domain 3 (SH3) patterns. Mutations in this gene cause familial juvenile nephronophthisis. View
GIMAP4 - This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. … View
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FGFR1OP - This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing … View
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FBXO38 - Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. May coactivate KLF7, but does not … View
SYTL4 - Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively … View
NOL7 - - View
CCL7 - This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a … View
CLEC7A - This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common … View
MELL1 - The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family … View
TTC7A - - View
WDSUB1 - - View
LEPR - Leptin (LEP; MIM 164160), an adipocyte-specific hormone that regulates adipose-tissue mass through hypothalamic effects on satiety and energy expenditure, acts … View
C10orf51 - - View
CCDC5 - Regulator of spindle function and integrity during the metaphase-anaphase transition. View
MAST1 - Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their … View
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