Gene:
nuclear receptor subfamily 5, group A, member 2
Gene ID:
197220
Symbol:
NR5A2
Species:
1000
Description:
Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May determine, the liver- specific activity of enhancer II probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in human embryonic development.