Gene:
CDC16 cell division cycle 16 homolog (S. cerevisiae)
Description:
This gene encodes a protein that is a homolog of Saccharomyces cerevisiae CDC16. This protein is a part of the APC complex that is composed of eight proteins and functions as a protein ubiquitin ligase. The APC complex is a cyclin degradation system that governs exit from mitosis. Each component protein of the APC complex is highly conserved among eucaryotic organisms. CDC16 and two other APC complex proteins, CDC23 and CDC27, contain a tetratricopeptide repeat (TPR), a protein domain that may be involved in protein-protein interaction.