Gene:
cylindromatosis (turban tumor syndrome)
Gene ID:
190894
Symbol:
CYLD
Species:
1000
Description:
Negative regulator of TRAF2 and NF-kappa-B signaling pathway. Has deubiquitinating activity that is directed towards non-Lys-48-linked polyubiquitin chains. The inhibition of NF- kappa-B activation is mediated at least in part, by the deubiquitination and inactivation of TRAF2 and, to a lesser extent, TRAF6.