Gene:
SET domain, bifurcated 2
Gene ID:
192465
Symbol:
SETDB2
Species:
1000
Description:
Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003).[supplied by OMIM]