Gene:
ATP-binding cassette, sub-family A (ABC1), member 9
Gene ID:
206420
Symbol:
ABCA9
Species:
1000
Description:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in monocyte differentiation and macrophage lipid homeostasis. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.