Viewing Gene


Gene: vanin 3
Gene ID: 191596
Symbol: VNN3
Species: 1000
Description: This gene product is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a secreted molecule whose exact function is not known. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Several transcript variants encoding different isoforms have been described for this gene.