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Gene: sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
Gene ID: 207418
Symbol: SPR
Species: 1000
Description: Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase; EC 1.1.1.153) catalyzes the NADPH-dependent reduction of various carbonyl substances, including derivatives of pteridines, and belongs to a group of enzymes called aldo-keto reductases. SPR plays an important role in the biosynthesis of tetrahydrobiopterin (see MIM 261640).[supplied by OMIM]