Gene:
Calcitonin gene-related peptide-receptor component protein
Gene ID:
209345
Symbol:
Species:
1000
Description:
Calcitonin gene-related peptide (CGRP; MIM 114130), a 37-amino acid neuropeptide, induces increased intracellular cAMP levels. This occurs when CGRP binds to a CGRP receptor (CRLR, or CGRPR; MIM 114190) after the latter is transported to the cell surface by RAMP1 (MIM 605153). CGRPR component protein, or CGRPRCP, modulates CGRP responsiveness in a variety of cell types.[supplied by OMIM]