Gene:
sin3-associated polypeptide, 30kDa
Gene ID:
203020
Symbol:
SAP30
Species:
1000
Description:
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48 and other polypeptides. This protein containing complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones.