Gene:
SMT3 suppressor of mif two 3 homolog 3 (yeast)
Gene ID:
200268
Symbol:
SUMO3
Species:
1000
Description:
SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002).[supplied by OMIM]