Gene:
malic enzyme 2, NAD(+)-dependent, mitochondrial
Gene ID:
200217
Symbol:
ME2
Species:
1000
Description:
This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene.