Gene:
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
Gene ID:
199626
Symbol:
CDIPT
Species:
1000
Description:
Phosphatidylinositol breakdown products are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. Two enzymes, CDP-diacylglycerol synthase and phosphatidylinositol synthase, are involved in the biosynthesis of phosphatidylinositol. Phosphatidylinositol synthase, a member of the CDP-alcohol phosphatidyl transferase class-I family, is an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus. Alternative splicing of this gene results in multiple transcript variants and protein isoforms.