Gene:
prostaglandin E synthase 2
Description:
The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.